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They can also be released based on the pathological changes of disease, meaning that low disease activity will restrict unnecessary drug release and extend the treatment effect lasting-time for inflammatory arthritis [116]
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Expression profiling of Arabidopsis orthologues, together with qRT-PCR validation of selected AaGLYs ( AaGLYI18, AaGLYI20, AaGLYII05, AaGLYII11, AaGLYIII01, AaGLYIII02 ) , revealed strong, time-dependent induction under salinity stress
Both compounds are dosed at 100-200 mcg administered 1-2 times daily via subcutaneous injection